During her acceptance speech Sunday, the star expressed her gratitude to have been able to "sometimes succeed and sometimes fail" over the years.

“The Substance,” “Wicked.” and “The Last Showgirl” were the big winners at the 12th annual MUAHS Guild Awards, held at The Fairmont Century Plaza Hotel. The Make-Up Artists and Hair Stylists ceremony was also livestreamed on YouTube and Vimeo.

Demi Moore won Best Actress for The Substance at Sunday’s Screen Actors Guild Awards, adding another wrinkle to the Oscar race. Moore, who was in first place in the Gold Derby odds, beat Mikey Madison (Anora),

Demi Moore called her her fellow actors "my greatest teachers" after she won the 2025 SAG Award for outstanding performance by a female actor in a leading role for her performance in 'The Substance' on Sunday,