The introduction of ATRA had prompted several study groups to explore the role of ATRA either as a single agent or in combination with chemotherapy. Although treatment with single-agent ATRA ...

One significant study assessed the safety and efficacy of a chemotherapy-free regimen combining ATRA and ATO in pediatric patients with APL. The results indicated that this approach led to ...

Atara Biotherapeutics (NASDAQ:ATRA) has announced plans to cut around 50% of its workforce, just a little over a week after it said the FDA had declined to approve its immunotherapy Ebvallo.

Although treatment of newly diagnosed APL with anthracycline-based chemotherapy combined with ATRA has been shown to be highly effective, limiting exposure to cytotoxic chemotherapy and ...