Cannabinoid receptor 1 (CB1) is the best-characterized cannabinoid receptor, and CB1 antagonists are used in clinical trials to treat obesity. Because of the wide range of CB1 functions, the side ...
• Anti-CB1 inhibiting antibody, nimacimab, showed greatest peripheral restriction compared with monlunabant and rimonabant, small molecule-based CB1 inhibitors, which both exhibited increasing ...
The endocannabinoid system is the body’s system that regulates an array of other systems in the body. It works to maintain homeostasis by the use of receptors, cannabinoids, and metabolic pathways ...
June 9, 2011 (San Antonio, Texas) — Chronic marijuana smokers show a decrease in cannabinoid CB1 receptor activity, which correlates with the number of years of cannabis smoking, but the deficits are ...
A Chinese research team joined forces with Russian and U.S. biologists to obtain the crystal structure of the human type 2 cannabinoid receptor. Their findings will help develop drugs against ...
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