The derailment of two high-speed trains on Sunday has left at least 21 people dead in southern Spain’s Adamuz municipality, near Córdoba, the Andalusian Emergency Agency said.

A high-speed train derailed in southern Spain on Sunday, jumping on to the track in the opposite direction and hitting an oncoming train, the Spanish rail operator Adif said.

“The last units of the Iryo train heading toward Madrid have derailed, with those cars invading the opposite track where, at that moment, a Renfe train heading toward Huelva was traveling. The impact ...