Objectives Understanding the molecular changes in the preclinical synovium is crucial for identifying factors that drive ...

Objective Transcortical pores and the bare area have been suggested as structural determinants of bone erosions in rheumatoid ...

Objective The aim of this study was to investigate the relationship between antineutrophil cytoplasmic antibodies (ANCA) ...

Objectives The TREAT EARLIER trial showed in clinically suspect arthralgia (CSA) that methotrexate induced reductions in ...

Objective Sjögren’s is a chronic systemic autoimmune disease characterised by dryness symptoms (eyes, mouth, skin), alongside ...

Objective Insomnia often co-exists with hip or knee pain and is associated with greater pain severity. However, there is ...

Background Chronic pain due to osteoarthritis (OA) causes considerable burden, and current treatment options are limited. This phase III study aimed to compare the efficacy and safety of fasinumab, an ...

Background About 20% of female patients with anti-phospholipid syndrome (APS) experience obstetric complications despite standard treatment with aspirin and heparin. Treatment with hydroxychloroquine ...

Objective To examine the performance of the new 2022 American College of Rheumatology (ACR)/EULAR giant cell arteritis (GCA) classification criteria for diagnosis in routine clinical care. Methods ...

Objective(s) This study evaluated the interaction of anticitrullinated protein antibody (ACPA) and rheumatoid factor (RF) in predicting sustained clinical response in an observational registry of ...

Post-traumatic arthritis (PTA) develops after an acute direct trauma to the joints. PTA causes about 12% of all osteoarthritis cases, and a history of physical trauma may also be found in patients ...