Background: Determining optimal timing for intensifying the frequency of physician encounters for type 2 diabetes mellitus (T2DM) requires trade-offs between timely care and clinician burden. We aimed ...
Key points On Jan. 20, 2025, the incoming United States administration froze all foreign assistance funds for 90 days, including the President’s Emergency Plan for AIDS Relief (PEPFAR) funding.[1][1] ...
Multiple sclerosis (MS) often begins in early adulthood, and symptoms may include fatigue, pain, and mood changes. These may not be outwardly visible but can be deeply disabling.[1][1] Clinicians ...
More than 85 000 (2.3 per 1000) people in Canada have cerebral palsy, a group of disorders resulting from a nonprogressive brain lesion early in life. Seventy-five percent of those living with ...
A 68-year-old man presented to the gastroenterology clinic with recurrent melena over 3 months with a history of recurrent spontaneous epistaxis and a familial pattern of similar bleeding among his ...
Cardiovascular risk thresholds for intensifying primary care encounter frequency for patients with type 2 diabetes mellitus: a target trial emulation ...
Cytisine, primarily derived from the Cytisus laburnum plant (which inspired the development of varenicline), is a partial agonist of the α4β2 nicotinic acetylcholine receptor responsible for central ...
Most antihistamines are safe during pregnancy and breastfeeding Systematic reviews of observational studies show no association with adverse fetal or maternal outcomes with antihistamine use during ...
A 24-year-old man was brought by ambulance to a rural hospital after a motor vehicle collision. On physical examination, he was hemodynamically unstable with a blood pressure of 60/40 mm Hg and a ...
Diagnosis of loperamide abuse requires a high index of suspicion Loperamide is not detected by routine drug screens. Typically, a patient with loperamide abuse will have a history of opioid misuse or ...
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Semaglutide, liraglutide, lixisenatide, dulaglutide, and tirzepatide are the current GLP1RAs available in Canada. These are approved for the treatment of type 2 diabetes and obesity and have been used ...