Adames helped lead the Brewers to three playoff appearances from 2021-24 before the Giants signed him to a seven-year, $182 million contract.

With two outs and nobody on, Contreras drove a 1-0 pitch from Rodríguez (3-5) over the left-center wall for his first career walk-off homer, as the major league-leading Brewers (81-48) overcame a pair of solo home runs from Willy Adames in his return to Milwaukee.

Willy Adames hit two homers for the Giants in his American Family Field return but his old buddy William Contreras delivered a walk-off homer.