A local cancer treatment center is giving patients across West Texas renewed hope by highlighting the life-saving potential of clinical trials.

The Odessa American is the leading source of local news, information, entertainment and sports for the Permian Basin.

The Odessa American is the leading source of local news, information, entertainment and sports for the Permian Basin.

Russia launched two ballistic missiles toward the port of Odessa, resulting in the death of one person and injuries to eight ...

In observance of Memorial Day, the following City Offices will be closed on Saturday, May 24: Odessa Animal Shelter, Household Hazardous Waste, and the Odessa Recycling Center. City offices that will ...

For this week’s Basin Bites, we visited Brunch and Munch Eatery and Creperie, an Odessa gem that’s just as much about the ...

Odessa police arrested Cory Shane Castillo on multiple child sex crime charges after an investigation involving a local high ...

Texas kicks off its Click It or Ticket campaign, urging drivers and passengers to buckle up and avoid costly fines while ...

Cory Shane Castillo, 33, has been charged with sexual assault, child grooming and possession of child pornography.

The Odessa Police Department has arrested a fire fighter and instructor at Odessa College after an investigation that began with concerned parents. 33-year-old Cory ...

Local officials are once again considering forming a unified fire district to serve the Odessa area, according to WENY News.

Months after failing to form a new joint fire district in Schuyler County, Schuyler and Chemung County officials are laying the framework to try again to create the ...