Alkanediols such as 1,6-hexanediol disrupt many phase-separated condensates in cellula and in vitro, but how molecular interactions are perturbed by these compounds remains unclear. This study uses ...

Tda1 protein kinase, activated by Snf1 and yeast GSK3-β, fine-tunes metabolism through the phosphorylation of Hxk2, which is implicated in yeast glucose repression. Tda1 is activated by both Snf1 and ...

The gut microbiome supports health through balanced metabolic exchanges, but in type 2 diabetes rising blood glucose shifts interactions from cooperation to competition, altering cross-feeding ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Protein Kinase A (PKA) is regulated spatially ...

I was at a cancer meeting in Brisbane when the question about the culture of a community occurred to me. The meeting was well ...

This month's cover highlights the article AAV-mediated expression of proneural factors stimulates neurogenesis from adult Müller glia in vivo by Marina Pavlou, Thomas A. Reh and colleagues. Injuring ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Skeletal muscle wasting results from numerous ...

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Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Primary cilia are solitary organelles formed ...