Multi-modal data integration of single-nuclei RNA and ATAC sequencing with spatial transcriptomics, provides new molecular insights into gene regulatory networks driving cell state transitions in ...

Tda1 protein kinase, activated by Snf1 and yeast GSK3-β, fine-tunes metabolism through the phosphorylation of Hxk2, which is implicated in yeast glucose repression. Tda1 is activated by both Snf1 and ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Primary cilia are solitary organelles formed ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Colorectal cancer molecular signatures derived ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Protein Kinase A (PKA) is regulated spatially ...

I was at a cancer meeting in Brisbane when the question about the culture of a community occurred to me. The meeting was well ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Type 2 diabetes (T2D) presents a global health ...

This month's cover highlights the article AAV-mediated expression of proneural factors stimulates neurogenesis from adult Müller glia in vivo by Marina Pavlou, Thomas A. Reh and colleagues. Injuring ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Neurotoxins derived from animal venoms are ...