Intravenous thrombolysis remains a standard treatment for acute ischemic stroke within 4.5 hours after onset. Vascular reocclusion may occur after intravenous thrombolysis and may be preventable ...

Corporatization” of health care, a process predicted decades ago, now refers to the general trend throughout the industry toward higher levels of integrated control by consolidated profit-seeking ...

Musunuru and colleagues 1 describe in the Journal an innovative approach in which gene editing is applied in the treatment of a very rare disease, the severe urea-cycle disorder carbamoyl ...

A 63-year-old woman was evaluated for dyspnea and edema. Soft-tissue thickening was noted in the retroperitoneum and mediastinum and around the heart and vessels. A diagnosis was made.

Explore a collection of articles and other resources on the Coronavirus (Covid-19) outbreak, including clinical reports, management guidelines, and commentary.

The authors review the epidemiology, pathophysiology, and treatment of alcohol-associated hepatitis, including the evidence for glucocorticoids and liver transplantation.

Cancer of unknown primary site is an uncommon diagnosis that accounts for 2 to 4% of all cancers. 9 The American Cancer Society estimates that approximately 37,370 new cases of cancer of unknown ...

Spontaneous intracranial hypotension is a condition characterized by a lower-than-normal volume of cerebrospinal fluid (CSF) because of leakage of CSF through the dural membrane at one or multiple ...

This article reviews the presentation, diagnosis, and treatment of bronchiectasis, a syndrome of abnormal airways that results in chronic cough, sputum production, and respiratory impairment.

Pegcetacoplan was superior to eculizumab with respect to the change in hemoglobin level from baseline to week 16, with an adjusted (least squares) mean difference of 3.84 g per deciliter (P<0.001 ...

Family meetings encourage an ongoing exchange of information between clinicians and families. These meetings are also indicated when there is a change in the patient’s medical status, when ...