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0:21
YouTube
Chong Lab Science
Atomistic simulation of a complete protein-peptide binding pathway with rigorous kinetics
A representative binding pathway generated by weighted ensemble simulations involving an intrinsically disordered p53 peptide (gold) and MDM2 protein (gray). "Anchor" residues which become the most buried upon binding are highlighted in red, blue, and green for F19, W23, and L26, respectively. For further details, see http://pubs.acs.org/doi ...
2.2K views
Sep 19, 2016
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